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Clinical trial support

DDL offers advanced laboratory services as well as logistic expertise to support clinical trials.

DDL has extensive experience in a wide range of molecular biological techniques including multiple (real time) polymerase chain reaction platforms, Sanger sequencing, Next generation sequencing, complex data analysis and reporting as well as various multiparameter analysis platforms.

We are particularly experienced in the molecular analysis of infectious microorganisms such as hepatitis viruses (HBV and HCV), human papillomavirus (HPV), respiratory infections (RSV, Rhinovirus, Influenza virus), and herpesviruses (CMV, EBV, VZV, HSV).

DDL collaborates extensively with (bio)pharmaceutical and diagnostic companies in the areas of molecular testing related to novel vaccines (HPV, Rotavirus), antiviral therapies (HBV, HCV, RSV, Rhinovirus, Influenza, VZV and CMV.), and anti-bacterial treatment.

DDL offers microbiome analyses, using 16S rDNA based methods, as well as whole genome sequence analysis of isolated bacterial strains to support the clinical development of anti-bacterial therapies. This service can be combined with traditional culture-based microbiology diagnostic services.

DDL provides pathology services, especially in combination with molecular diagnostics, including laser capture micro-dissection. We offer digital scanning of microscopy specimens to permit worldwide electronic access for pathology examination.

DDL has extensive experience in analysis of complex diagnostic data sets (e.g., next generation sequencing) and can provide tailor-made data reporting solutions, including proprietary software tools, meeting the requirements of our sponsors as well as the guidelines provided by FDA and EMA.

Logistic support comprises design and production of sample collection kits, requisition forms as well as assistance in sample shipment and storage.

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